GeneWeb

GeneWeb - Consanguinity



This part explains the concepts of "consanguinity" and "relationship" used by GeneWeb and how they are computed.

Consanguinity and Relationship

The genom of an individual consists of a great number of genes which, if mutations are ignored, reproduce identically. The genes can be used to measure the identity of a person.

The genes are placed in precise locations named "locus". Each individual has for each locus two genes, one transmitted by his mother, the other by his father, and transmits to his children a copy of the one of his genes.

The Consanguinity of an individual x is the probability cg(x) to find in a given locus two identical genes.

The Relationship of two individuals x and y is the probability pr(x, y) to find in the same locus two identical genes.


Computations

A probability calculus shows that:


GeneWeb

GeneWeb displays the consanguinity and the relationship in the form of a percentage.

Statistically, on the great number of locuses of an individual, the consanguinity corresponds approximately to the percentage of his locuses holding identical genes.

The algorithms of consanguinity and relationship were written by Didier Rémy, director of research at INRIA. We thank him for that.


References



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